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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f9dbad71a7d9f132a767ac7fd8f606e8e433fcebc85c1f9652ec573d558cf6c' 
  AND token = '1xia/SrGf/7mw5ULKCcxuBwpyNpPS0pkaXLIMioXoFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}