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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6528d254e479c45b5ec56b83dbd51aeac3bba3a2aa16f257736ea5d12b2d78b1' 
  AND token = '0TZ/PUGMhHDcyS6MoMx7TMIJCuxXSid+2z2ekQIurxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}