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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eeea3648dfc575dd626812c4a508af3ab0ae702dacc96c6b8c28f7b9b3c8f7a' 
  AND token = 'fII3MXv8WEonrqd5YP7RyVJLp23vwfOnlJMg6T2Etx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}