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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cb3d91b9c435a1b7cbe9e0aaaf3efa8ebb4f1e9f3d7ff078e4863a3bac2d4ac' 
  AND token = 'w4NuBWA8ciUw+FWGw2pd8FQcF2q1VDTKuzaFFCFiqwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}