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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '824b1b85cd1b173af3deccb8ca044b722976d349cf5e8709f9246cf7edeb11bc' 
  AND token = 'xnisZYRw6Op/OduDtwK8muVo52GupCIl9dm5WbnAnr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}