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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c31c10d744182b1be730d5497802fca0c466fbe1a04749c9d0760035998db945' 
  AND token = '+zVvO9XMvymHjuM6++4iAsQTfTOfAr6SaN1gMdKOGCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}