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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8c7da3104c134dd1f2cb54013dc20456466013db8cc150c756328668b2e80c2' 
  AND token = 'jgM5qbV+9Wezl78ITHNamDriA+WgN2Tfj4JxOhcG1J0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}