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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b3affee1a424d5a540baec5d25a53163ba7e4099277981ac80b8dbc035b259f' 
  AND token = 'TsrMMeku4Nic5vCyfN4vGqUwStZKmqRCsrJQnnmUYq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}