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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16dd8014260dfb81a5ee65c1d89f6742a917b2d41a4b465c310f939ba5c43180' 
  AND token = 'v1JIUozmNWIfOTnexceDXyDDYjCbZUk5HVTRUHxYXEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}