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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80ad78037f80e41288abb90317af5c5b21947bf7cb7b7b6461d8acb690d55790' 
  AND token = 'goahjSFcZ5szuT0gGPHBR3Df3Lxa/lx1whInlXftb7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}