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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65744c18e6a8d0870ba0cc1e9ca950beaa239669c45d6bfd06c9710dfce7df91' 
  AND token = '8wB3ZfoOAKzNdGEQU/5l5AzhkO3vab35+WVQZ5NUNLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}