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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07149dd822dc9e9533f65672a1cfa4b416c86f7f3db1eb7ebcda3db2ccce5a4b' 
  AND token = 'cmjRWkKnCy7dXNuOAtv9cK4bOniP9lqMeBeX8N+/24Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}