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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a9f4ed047243918033dcd7384b5974059c019cd78c364c5a22571760f02d219' 
  AND token = 'AjsEAV8dXZCTbO2Opu8yLv0x6tj0z1uJxdpzGBwSnYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}