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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00229a81868e3931c1f6fd30bda843d6be627c1a811c5e1e6f5ef7cafae22120' 
  AND token = 'r5s9vs4BI6rU/h9mZOO+oGCBPzWlU7z23FH64qt0TrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}