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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c28619aa8b70a8da926df3781183fb4846806a910d167dcb892e039e3f273109' 
  AND token = 'J7b8P2MoUlkHZ1lLxi/JgQmRZ4yNJiYwTEiedRhmP1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}