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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37a8f151ac3e330123bb90d8c80fb35c33ef6ad32d9476cc080ef70888843e66' 
  AND token = 'ay6Jv8zskvy7pj69TMBdvNY3stb+fIQ+bsjsagwLsPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}