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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6e074ac523eb6045a64722f04e249706421e0543e839ba092915bc61f9661c4' 
  AND token = 'gONCOexlGA3tuxOtc1S8mf+fFZkMrRhlmYTgVODT5eA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}