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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a6003e7a3c4b98e28ba4fe30c2868a52a953f991267a5ff283e87d338d560e9' 
  AND token = 'IWHu1RNrjyvRbKftp86Q4pBMbYJ/A3nHSoUpdSjW9VU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}