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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '150c61f719f52f49b8763c39863f1e0956dfe20c87836010535beee40a0d8f3d' 
  AND token = 'ASHdz0VMWg21zTRjrNH0JeVVfUHrU8jRnFZ01l3W0+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}