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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c6c4e40667f063d4bdb221c018eba10e56b69075d507b83c4fb39a51ac4d91f' 
  AND token = 'zCTXngzhnHhCRwMUzTOTQW6GRMdFEFIXS8ubsa50xQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}