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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed7a8441570d535bdaea536e5f04ecc2344e614811bb9e9c6ce2d52edd2c1154' 
  AND token = 'qFqALEoJDL+V/X9Y3ieMU2DNSvPnpTYz36OK/6vFD8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}