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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd15de00b63857d3eebfc1805566d1796c0d9d4d3002fa5037cb481c5f6613c51' 
  AND token = 'w0ZdOe+qKjtFjyQwCL+MKeJ51XbIK5J93ARoVhL0VQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}