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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cffc8cacb6d8aed01175e2ee5c90464c0656038c2116529350e62a1b188e6ce8' 
  AND token = 'ZfmyGjh/J5IeXYiOLE6aXG6+/D9rPcCKntQn/ebqC4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}