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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afd09a98a4a066332884cd9d6c58dae0fa9b3393f0bf53e914f19aa7cc1e9729' 
  AND token = 'k5NDOk6UwUg3H4gulO4n986XWC0XvTwSErePt8D8iYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}