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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34abb32ad8d5062972522eafc9b07ae58bbe8b3a8f3e327e36021d4b0a685479' 
  AND token = 'Hs427BQr5iKwWdYe1v+b2Y0jN46nQsjA/rqU0xMJz7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}