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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e3fd6dd9af427480c73d9e72d8a89c76f44c42226567046f4c4ad82c701bff7' 
  AND token = 'bJY1oD5nbuJV0zVAxchzpVupyjFUczikM97PWpsuI0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}