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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '270df5f583a4804d77fc4f1cd9badfdad69a68ef646c4dd3901574fd464ead97' 
  AND token = '8ezWl5LT3+bM6/BnUl1lEvaiTsS3Knibbl2pWFmANvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}