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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd07e59cae9ed9f5658fb2c52254de59a36a90e646f165af1af26c5d80aa81e0f' 
  AND token = 'zmnJhs7AJGrSp1LsIW1tQkMQe+3I6QRr+kxzpp5Wroo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}