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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aacc75880416b308f98bfd2586c24082f97dee0179ac17fe18a1033c4ce8fdad' 
  AND token = 'XRSD1IMFL0aA215KNeiFVVD4MMOODPpv9+ya+emyjsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}