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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ad9b2b576eaf08538d4807b4174075946e78aad42d90d841ae166f08df8d9b2' 
  AND token = 'HTul9giWq8VPYKj2KMRuZM51F4ZSAeWSQDjezz9n0Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}