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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68182df91add35efedad027eb1a329bd0c3ce318040dd32bbfdfb8067f6aa745' 
  AND token = 'uCLIeMaaGtt60P0KPPDp3f0WAYZGB4UaRXFqa+T2BjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}