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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af4680c2a4a6ef3551ae5675721c293d21c891a86132b0414714326653dc9bfa' 
  AND token = 'MB+18WGe93moA6qiXYOopUYminkPCCtEHA1sD+XfT6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}