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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7149174251b60d3b8c8ddf330349b1f2a9c2dff2f1a067b77fed5df0475e018' 
  AND token = 'Xvqj7TDSEIfOYn8/QyDmXrdatiow0RT+Dqgc3Ufn/dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}