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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35a16db9bb2da32cbb0e72b1668c47adf53e7bc3acbc0f736a7df03d3482b4e0' 
  AND token = 'oqmHNazOttOj87xYxS/dCg2UT2b4zBVyMNJ8fieZMi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}