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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e9423f902ea8d6c6c9dac9e1c2b18708337afcb8acbecadd560aea9213b2099' 
  AND token = 'xHhjx7Af07b9abAPYjzh/gmHrChE6+MUFLseNYoCPmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}