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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb264dc0fe002a0cece317ede5d3f97a3dd8b760dc381f2f1d1b592b5289ce19' 
  AND token = 'eJvH9gcEpJWDYdHardat5nI/SZSYPJLYb4dj8FDWZQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}