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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afd8fcb4a5c72168502647d3975630fbe506e5c801844522d2b52b0bdb5c6dc6' 
  AND token = 'X2lFB2ObJ2MJQYYxRTFjGuGYdsdfIIx9Xc5bRjtcpsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}