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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e4c6456df3199e2ee840707461891990c8bd70bc12e8e7a7a098ec7a0a56634' 
  AND token = 'GXFiZ4Rer5rVdLRUT7aLsamLlVlBQ2NxmMJq21GzdIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}