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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a1272b3bcb9d6f6a5db7ad189c0a113e2d2d16100bc0074ddc06c48eb8a4a59' 
  AND token = '73FgLRBxt6MTJBjHcS1gqf1AwbgYLU1QjyqyVhxbOQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}