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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '753850ba9c83e7b5f2a55aefce9b42312269144dea0ea45f3750a920c819fc08' 
  AND token = 'tAsBJTnBNa3m2Ll+mOYI8aTKt1PkgBccaytGvyTRwOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}