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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d4158ece95d1e138f575f7b4439807fc50cda6aaeefa84ed92639a16f6e1aba' 
  AND token = '6Xjsm2X+gc/r10B05+R0/Diefb7d6/aFvHMXUAknSMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}