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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e847cbd021a1e626f654a7be6bd7212bbc6460652c402795034acbf5b5df281a' 
  AND token = 'w6PV41T76CXE6RZyF5ctZqEQjnY5zWrWTTVSFBIvof4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}