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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00177adecca0a507fa256fff5ae087b4cfb81573504989f1d73865e7f7eed3c6' 
  AND token = '1eq95ycw2eU6djkcrRUvOvwszMGtadCExiulUn0yXNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00092

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}