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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a10b011e7663742c60b2284f8ca5e6199c7e5e8389035fd3468949b36f0d302' 
  AND token = 'mN0Bdl5IpvuXhjPNb0XVi4Ix7L8UX/dRM6D6WimgGjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}