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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35bc272f600ebe4fbe252e5306e10dc2b8bad1bc79c897436e842b2319971263' 
  AND token = 'xZyRIaciH/DqZs6bxK4c+XByhtTSQ6E13NCjBsiWXvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}