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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2727748adffb60be81d6c8eed1b4e5c345d01e2716fdf53c355cd7810af7a404' 
  AND token = '74dNHoOhdyoZ24dv0IUrpn3/mk2efu6zHo6NgnxDrRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}