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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2582d0d1248af5f18177e73a7f2cbfdda14beec3a4d10e427b4c7be62e34660' 
  AND token = 'bEnl5Y9RGKqoBKp0UvydNL5T/qfKkZzYkzrckDI6Hw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}