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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dd0344e27d3a323a05cd44a23ad9dc2ffcd92ff42a6bde4ecbfa234ea6be641' 
  AND token = 'sZ7ihCvNXLVrQyFaG4TeFOVrh+36ecvJJZw+tl9kLgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}