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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bffe4a9dbd22fe6437daa4bceaf4e257116f240129699570355b18365ad08ec' 
  AND token = 'GtmwqkLjzsAjRiWA2Z1HgxRgU4XnyQ0Sb08oBtMcz14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}