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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0250ad7cea0024f6f188c2a61fc55697e7a3351cfa7436e62d61feb56aae9d8a' 
  AND token = 'RHIpIM7ZGjuUEMhSimRiv625Y5b6fZpDr3MbrvdRDdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}